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Carlos Gonzalez-Cabezas Carlos González-Cabezas, D.D.S., Ph.D.
Associate Professor

Carlos González-Cabezas, DDS, PhD, holds the position of Associate Professor (tenured) in the Department of Preventive and Community Dentistry at Indiana University School of Dentistry (IUSD). He serves as Director of the Preventive Dentistry MSD/MS Programs, the OHRI Laboratory Research Core/Facility, and the OHRI Laboratory Contract Testing Program.  Dr. González-Cabezas also directs the Digital Electron Microscopy Facility of IUSD; and the Secondary Caries and Remineralization Research Programs within his department. After receiving his dental degree from the Universidad Central de Venezuela (UCV), Caracas, Venezuela, in 1991, Dr. González-Cabezas worked as a Research Collaborator for the Dental Research Institute of his Alma Mater (UCV) for almost two years, while simultaneously working in private practice. In 1992, he entered the PhD program in Dental Sciences at Indiana University. In 1995, he accepted the position of Director of the Confocal and Scanning Electron Microscopy Facility. In 1996, he accepted a position as Visiting Assistant Professor at IUSD. In 1997, he obtained his PhD degree in Dental Sciences at Indiana University. In 1998, he accepted a tenure-track position as Assistant Professor at IUSD. Between 1999 and 2001, he served as Vice-President and President of the Indiana Section of the American Association for Dental Research.  In 2002, he obtained a 2-year certificate in graduate operative dentistry. In 2004, he obtained a D.D.S. degree from Indiana University School of Dentistry, became licensed in the state of Indiana, and was promoted to Associate Professor with tenure.  In September 2005, he accepted the positions of Director of the OHRI Laboratory Research Core/Facility and Director of the OHRI Laboratory Contract Testing Program.
 
Publications

Thneibat A, Fontana M, Cochran MA, Gonzalez-Cabezas C, Moore BK, Matis BA, Lund MR. Anticariogenic and antibacterial properties of a copper varnish using an in vitro microbial caries model. Operative Dentistry 2008;33(2):142-8.

Totiam P, González-Cabezas C, Fontana M, Zero DT. A new in vitro model to study the relationship of gap size and secondary caries. Caries Res 2007;41:467-473.

Metz MJ, Cochran MA, Matis BA, Gonzalez C, Platt JA, Lund MR. Clinical evaluation of 15% carbamide peroxide on the surface microhardness and shear bond strength of human enamel. Operative Dentistry 2007;32(5):427-36.

Zero DT, Hara AT, Kelly SA, González-Cabezas C. Evaluation of a desensitizing test dentifrice using an in situ erosion remineralization model. J Clin Dent 2006;17(SI):112-6.

Hara AT, Ando M, González-Cabezas C, Cury JA, Serra MC, Zero DT. Protective effect of the dental pellicle against erosive challenges in situ. J Dent Res 2006 85(7):612-6.

Hara AT, Turssi CP, Ando M, González-Cabezas C, Zero DT, Rodrigues AL Jr, Serra MC, Cury JA. Influence of fluoride-releasing restorative material on root dentine secondary caries in situ. Caries Res 2006;40(5):435-9.

Clarkson B, Fischman S, Maltz M, González-Cabezas C, Uemura M, Schulte A, Carvalho J, Acevedo AM, Schafer F, Chesters R, Elwood R. 2005 Indiana Conference Workshop Session: Chesters Model. In: Clinical Models Workshop: Remin-Demin, Precavitation, Caries. Ed. GK Stookey. 2005:259-61.

Hara AT, Ando M, Cury JA, Serra MC, González-Cabezas C, Zero DT. Influence of the organic matrix on root dentine erosion by citric acid. Caries Res 2005;39:134-8.

Fontana M, Haider A, González-Cabezas C. Caries lesion development and biofilm composition responses to varying incubation times and sucrose exposures. Biofilms 2004;1:229-37.

Sá L, González-Cabezas C, Cochran M, Matis B, Fontana M, Moore K. Fluoride-releasing materials: Their anti-cariogenic properties tested in in vitro caries microbial models. Oper Dent 2004;29(5):524-31.

Ando M, González-Cabezas C, Isaacs RL, Eckert GJ, Stookey GK. Evaluation of Several Techniques for the Detection of Secondary Caries Adjacent to Amalgam Restorations. Caries Res 2004;38:350-6.

Schemehorn B, González-Cabezas C, Joiner A. A SEM evaluation of a 6% peroxide tooth whitening gel on dental materials in vitro. J Dent 2004;32(S1):27-34.

Eggertsson H, Ferreira-Zandoná AG, Ando M, González-Cabezas C, Fontana M, Martínez-Mier EA, Waskow-Chin JR, Jackson RD, Eckert GJ, Stookey GK, Zero DT: Reproducibility of in vitro and clinical examinations with QLF (Quantitative Light-induced Fluorescence). Developing guidelines for imaging and analyzing QLF- images, and a process for training examiners. In: Stookey GK, ed. Early detection of dental caries III: proceedings of the 6th annual Indiana Conference. Indianapolis, Indiana: Indiana University School of Dentistry 2003:213-228.

González-Cabezas C, Fontana M: Current research using new technologies for the detection and monitoring of secondary caries. In: Stookey GK, ed. Early detection of dental caries III: proceedings of the 6th annual Indiana Conference. Indianapolis, Indiana: Indiana University School of Dentistry 2003:347-362.

González-Cabezas C, Fontana M, Gomes Moosbauer D, Stookey GK: Early Detection of secondary caries using quantitative light-induced fluorescence. Oper Dent 2003;28:415-422.

González-Cabezas C, Li Y, Gregory RL, Stookey GK.  Distribution of cariogenic bacteria in carious lesions around tooth-colored restorations.  Amer J Dent 2002;15:248-51.

Fontana M, Gonzalez-Cabezas C, Haider A, Stookey GK: Inhibition of secondary caries lesion progression using fluoride varnish. Caries Res 2002;36:129-135.

Stookey GK, Gonzalez-Cabezas C: Emerging methods of caries diagnosis. J Dent Educ 2001;65:1001-1006.

Platt JA, Almeida J, González-Cabezas C, Rhodes B, Moore BK. The effect of double adhesive application on the shear bond strength to dentin of one-bottle adhesive systems. Oper Dent 2001;26(3):313-317.

Zero DT, González-Cabezas C, Fontana M.  Oral Factors to Consider that Influence Restorative Treatment.  In: the changing practice of restorative dentistry.  Ed. S. Duke. 2001: 87-103.

Fontana M, González-Cabezas C.  Secondary caries and restoration replacement.  An unresolved problem in dentistry.  Compendium 2000;21(1):15-30.

González-Cabezas C, Fontana M, Gomes-Moosbauer D, Ando M, Analoui M, Stookey GK. Comparative studies of several methods for the early detection of secondary caries.  In: early detection of dental caries II.  Ed. GK Stookey.  2000:317-342.

Fontana M, Yanikoglu FC, Ozturk F, Ando M, Hayran O, González-Cabezas C, Haider A, Baldridge L-A, Stookey GK. Comparison of QLF, ultrasound and confocal microscopy in the measurement of demineralization/remineralization of enamel lesions developed on natural smooth surfaces. In: early detection of dental caries II. Ed. GK Stookey. 2000:301-316.

Fontana M, González-Cabezas C, Stookey G. QLF monitoring of therapies for early secondary caries arrestment and remineralization.  Proceedings of the society for photo-optical instrumentation engineers: Progress in Biomedical Optics, Lasers in Dentistry VI, 2000;1(4):261-268.

Fontana M, González-Cabezas C, Wilson M, & Appert C. In vitro evaluation of a "smart" dental material for its efficacy in preventing secondary caries using a microbial artificial mouth model. Am J Dent 1999;12(SI):S8-S9.

González-Cabezas C, Li Y, Gregory RL, Stookey  GK.  Distribution of three cariogenic bacteria in secondary carious lesions around amalgam restorations.  Car Res 1999;33:357-365.

González-Cabezas C, Fontana M, Stookey GK. Measurement of mineral gain and loss on dental enamel and dentin using confocal microscopy. Methods of enzymology 1999;307:485-496.

Eggertsson H, Analoui M, van der Veen MH, González-Cabezas C, Eckert GJ, Stookey G. Detection of early interproximal caries in vitro using laser fluorescence, dye-enhanced laser fluorescence, and direct visual examination. Caries Res 1999:33(2):227-233.

Stookey GK, Isaacs RL, Ferreira Zandoná AG, Ando M, González C, Mau MS, Kelly SA, Analoui M: Clinical Validation of the Use of Fluorescence for the Early Detection of Dental Caries; in Featherstone JDB, Rechmann P, Fried D, and Katzir A (eds): Proceedings in Lasers in Dentistry V (vol 3593). Bellingham, Wash., SPIE—The International Society for Optical Engineering, 1999, pp 154-157.

Gonzalez-Cabezas C, Fontana M, Dunipace AJ, Li Y, Fischer G, Proskin HM, & Stookey GK. Measurement of enamel remineralization using microradiography and confocal microscopy. A correlational study. Caries Res 32:385-392,1998.

González-Cabezas C, Li Y, Noblitt TW, Gregory RL, Kafrawy AH, Stookey GK.  Detection of mutans streptococci in secondary carious lesions using immunofluorescent techniques and confocal laser scanning microscope.  Car Res 1995;29:198-203.

Fontana M, González-Cabezas C.  Topical application of Stannous Fluoride inside of cavity preparations: A review of the literature.  Ind Dent Assoc J 1995;Fall:22-4.

González-Cabezas C, Fontana M.  Uso de floruro tópico en las cavidades como medida preventiva de caries secundaria (English translation: Uses of topical fluorides applied to cavities as a preventive measure for secondary caries).  Acta Odont Venez 1993;31:55-58.

González-Cabezas C, Fontana M. Estudio epidemiológico de desnutrición y caries en un área marginal de Caracas (English translation: Epidemiological study on malnutrition and caries relationship in a poor area of Caracas). Acta Odont Venez 1992;30:29-33.

González-Cabezas C, Fontana M.  Uso de floruro tópico en las cavidades como medida preventiva de caries secundaria (English translation: Uses of topical fluorides applied to cavities as a preventive measure for secondary caries).  Acta Odont Venez 1993;31:55-58.
 
Education

Dr. Gonzalez is greatly involved and interested in the teaching of cariology to pre-doctoral and graduate students. He is the director of our MS/MSD graduate program in Preventive Dentistry. In addition to direct several graduate courses, he gives numerous lectures, seminars, and laboratories for both groups of students. Additionally, he regularly mentors students conducting research projects in cariology.  Dr. Gonzalez is also interested in developing and integrating new teaching methods to improve the education of dental students.
 
Research

Dr. Gonzalez research interests are mostly related to increasing our understanding of dental caries and erosion and their clinical management. He is regularly engaged in numerous research projects; many of them in collaboration with other institutions from all over the world. Dr. Gonzalez has particular interest in Secondary Caries (he is the director of this research program), dental erosion-abrasion, remineralization, fluorides, and oral health products in general (e.g., dentifrices, rinses, toothbrushes, etc.)
 
Contact Information

Phone: (317) 274-8822
Fax: (317) 274-5425
Email: cgonzale@iupui.edu
 
Indiana University School of Dentistry
Oral Health Research Institute
415 Lansing St., Indianapolis, IN 46202
 
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