Long regarded by academic peers and industry as a leading
center for preventive dentistry research, the Oral Health Research Institute has served as
Indiana University School of Dentistry's core
research facility for over four decades. OHRI clinical and laboratory research
facilities support a wide range of studies including, caries and erosion preventive agents, anti-plaque
and anti-gingivitis agents, anti-calculus agents, stain prevention
and removal agents, and whitening/bleaching agents.
Beginning with stannous fluoride toothpaste, the first clinically proven decay preventive formula,
OHRI has an impressive portfolio of clinical trials and testing capabilities that has
contributed significantly to dental health in the U.S. and abroad. This self
supporting institute was created without government funding and has a
distinguished reputation for its top-notch performance as a testing center for a
wide variety of dental products. OHRI employs over 70 full-time faculty
and staff members which can be increased with additional temporary
employees, depending on the needs of
each study.
As a unique extension of Indiana University School of Dentistry's
research capabilities, supported by the faculty of the Department
of Preventive and Community Dentistry, OHRI can meet investigator's
research and testing challenges by offering the following test-site advantages:
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Leader in dental research since early
1970's
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All studies conducted in compliance with FDA Good Laboratory
and Good Clinical Practices
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Reliable laboratory and bioresearch
models that have significant relevance to the oral environment
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Site of clinical trials of the first
fluoride-containing dentifrice and effective tartar control dentifrice
systems
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Pioneers in the development of
controlled clinical studies relating to the performance of restorative
materials in the oral cavity and testing of tooth whitening agents
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Access to a large patient population of
suitable project subjects; (IUSD developed patient pool of over 45,000
individuals)
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Convenient midwestern location at the
"Crossroads of America"
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